에디터 소개글

학술 분야 작가, 에디터, 리뷰어이며, 22년 이상의 학술 연구 및 강의 경험을 보유하고 있습니다. 학술 글쓰기 분야에서 폭넓은 경험을 쌓았으며, 영향력 높은 저널에 여러 논문을 게재했고, 다수의 연구 보조금 신청서를 제출하여 성공적인 결과를 얻었습니다. 보조금 신청서와 저널 논문의 전문 피어리뷰어이며 여러 학술 저널의 다양한 형식과 스타일에 익숙합니다.

전문분야

Biochemistry, Chemistry

학력

PhD, Biochemistry, University of Cambridge BSc, Biochemistry & Chemistry, University of Sheffield

출판경험

(2015) Mutational analysis of the Notch2 negative regulatory region identifies key structural elements for mechanical stability. FEBS Open Bio. 5, 625-633. (2012) Direct observation of proteolytic cleavage at the Sw site upon forced unfolding of the Notch negative regulatory region. Proc Natl Acad Sci U S A. 109(41): E2757-65. (2012) Cis-acting ribozymes for the production of in vitro transcripts with defined 5’ and 3’ ends. Methods Mol Biol. 941, 83-98. (2011). Su(dx) E3-Ubiquitin ligase dependent and independent functions of Polychaetoid, the Drosophila ZO-1 homologue. J. Cell Biol. 192:189-200. Interactions between subunits of S. cerevisiae RNase MRP support a conserved eukaryotic RNase P/MRP architecture. Nucleic Acids Res. 35, 6439-50. Specificity and autoregulation of Notch binding by tandem WW domains in Suppressor of Deltex. J. Biol. Chem. 282, 29032-42. Isotopically discriminated NMR spectroscopy: a tool for investigating complex protein interactions in vitro. J. Amer. Chem. Soc. 129, 6528-35. (2005). Secondary structure probing of the human RNase MRP RNA reveals the potential for MRP RNA subsets. Biochem. Biophys. Res. Comm. 335, 314-321. (2005). Probing the structure of Saccharomyces cerevisiae RNase MRP. Biochem. Soc. Trans. 33, 479-481. (2004). A conserved element in the yeast RNase MRP RNA subunit can participate in a long-range base-pairing interaction. J. Mol. Biol. 341, 375-388. (2004). The structure and dynamics of tandem WW domains in a negative regulator of notch signaling, suppressor of deltex. J. Biol. Chem. 279, 34991-35000. (2003). General plasmids for producing RNA in vitro transcripts with homogeneous ends. Nucleic Acids Res. 31, e82. (2002). Effect of magnesium ions on the tertiary structure of the hepatitis C virus IRES and its affinity for the cyclic peptide antibiotic viomycin. Biochemistry 41, 5383-5396. (1999) Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. Cell 96, 375-387. Hughes, M., Zhang, C., Avis, J.M., Hutchison, C.J. and Clarke, P.R. (1998) The role of the ran GTPase in nuclear assembly and DNA replication: characterisation of the effects of Ran mutants. J. Cell Sci. 111, 3017-26. (1996) Ran, a GTPase involved in nuclear processes: its regulators and effectors. J. Cell Sci. 109, 2423-7. (1996) Two structurally different RNA molecules are bound by the spliceosomal protein U1A using the same recognition strategy. Structure 4, 621-631. (1996) Solution structure of the N-terminal RNP domain of U1A protein: the role of C-terminal residues in structure stability and RNA binding. J. Mol. Biol. 257, 398-411. (1995) The RNP domain: a sequence specific RNA binding protein involved in processing and transport of RNA. Trends Biochem. Sci. 20, 235-240. (1995) Crystallization of RNA-protein complexes. I. Methods for the large-scale preparation of RNA suitable for crystallographic studies. J. Mol. Biol. 249, 398-408. (1993) Use of binding energy in catalysis: optimization of rate in a multi-step reaction. Biochemistry 32, 5321-5326. (1993) Reaction of modified and unmodified tRNA(tyr) substrates with tyrosyl-tRNA synthetase. Biochemistry 32, 5312-5320.

경력

Postdoctoral Scientific Staff, MRC Laboratory of Molecular Biology, Cambridge. MRC Research Training Fellow, MRC Laboratory of Molecular Biology, Cambridge. Postdoctoral Research Assoc., School of Biological Sciences, University of Manchester. Lecturer in Biochemistry, University of Manchester Institute of Science & Technology (UMIST). Senior Lecturer in Biochemistry, University of Manchester Co-Director of Bellingham Camping Limited, owner of Bellingham Camping & Caravanning Site in Bellingham, Hexham, Northumberland, United Kingdom.